Biosensors involve the integration of a biological recognition molecule with a physical or chemical transducer such that the biomolecule can be exploited for transduction purposes this basic idea has seen myriad developments and a fast expanding literature of all the niche areas in vivo monitoring is one where few other technologies can . Note citations are based on reference standards however formatting rules can vary widely between applications and fields of interest or study the specific requirements or preferences of your reviewing publisher classroom teacher institution or organization should be applied. Biosensors for real time in vivo measurements at the poc is nonetheless anticipated to shift this trend towards on body or and in vivo technologies and continuous glucose monitoring . In vivo biosensors are emerging as powerful tools in biomedical research and diagnostic medicine distinct from labels or imaging in vivo biosensors are designed for continuous and long term monitoring of target analytes in real biological systems and should be selective sensitive reversible and biocompatible due to the challenges associated with meeting all of the analytical . For this reason elaborate research efforts have been devoted to the development of a glucose sensor for the continuous in vivo monitoring of glucose although the use of microdialysis as a sampling interface between the body and the biosensor is widely accepted a major drawback of conventional microdialysis is the limited in vivo recovery
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